I am interested in the brain
mechanisms subserving goal-oriented behavior, that is, those
related to higher cognitive functions. Mostly attention, working
memory and auditory perception. In particular, I am currently
interested in how goal-oriented behavioral programs interact
with the environmental input, that is, how top-down processes
interact with bottom-up, stimulus-driven processes.
A good example of this interaction
is provided by involuntary attenion: unexpected novel stimuli
can capture our attention involuntarily, provided thay they
interact with the mental set of our ongoing activities. My
current experiments manipulate distractor features, irrelevant
stimulus-main taks contingencies, stimulus significance, and
working memory load, and we measure brain activity, either
as ERPs, MEG or more recently fMRI. And of course, I do keep
some interest in how all these process can become altered
in different states of brain pathology or mental disease,
and this is why I still do clinical research, particularly
in children suffering from different neurodevelopmental disorders. |
Drawn on our previous experience
and results, we are now undertaken new research challenges
for the upcoming years.
First, in cooperation with Prof.
Manfred Herrmann of University of Bremen and Prof. Mark Greenlee
of University of Regensburg, both in Germany, we are trying
to combine the more spacial accurate information on functional
magetic resonance imaging with the better time resolution
of biomagnetic brian signals to unraveal the spatio-temporal
neurodynamics underlying auditory distraction.
We second are now jumping into
a more “wet” cognitive neuroscience as we plan
to take blood samples from our healthy volunteers in order
to underpin the genetic determinants of distractibilty. This
research is being conducte with Prof. Imma Clemente of our
same Deparment of Psychiatry and Clinical Psychobiology, University
of Barcelona.
And third, since several electrophysiologic
phenomena within the auditory system, as the mismatch negativity
ERP, the gating (in and out) of the P50 middle latency auditory
ERP, and the habituation and dishabituation of the so-called
novelty neurons of the auditory pathway reflect change detection
in the auditory input, we now are trying to set the requirement
and manifestations of a “novelty system” in audition.
That general novelty system may subserve two cognitive functions
in audition: 1) organization of the auditory input in meaningful
chunks of information, and 2) drawing attention involuntarily. |